For the final paper in evidence-based practice, my group decided to research the question of whether or not the use of epidurals reduces the rates of postpartum depression in pregnant women. Through researching reliable databases and scholarly articles, we gathered conducted research to reach our conclusions about epidural use and postpartum depression. From all the conducted research analyzed, it is found that pain relief is associated with a reduced risk of postpartum depression, but specifically using an epidural analgesic does not have a direct effect on postpartum rates. These articles analyzed show that further research must be conducted to find a stronger association with epidural use and postpartum depression. Post partum depression is a real issue for women, affecting around 10-15% of women in the world. This research topic and analyzation was done so that risk factors and treatments for postpartum depression could be further sought; Which would help make the birthing process more efficient and comfortable for women.